|Personalized Medicine for Brain Tumors|
The Pacific Pediatric Neuro-Oncology Consortium (PNOC) is a network of more than 20 children’s hospitals
that conduct clinical trials of new therapies for children with brain tumors with the mission to identify personalized treatment challenges.
PNOC was formed to provide children with brain tumors access to individual and personalized treatment based on the molecular biology and genetics of each tumor.
Participating hospitals include:
PNOC is running clinical trials like nanoliposomal irinotecan and immunotherapy vaccine (H3.3K27M) for Diffuse Intrinsic Pontine Glioma, modified measles virus for recurrent medulloblastoma, Everolimus for recurrent or progressive low-grade gliomas, Vemurafenib for children with recurrent/ refractory BRAFV600E-mutant gliomas.
To find out if your child is eligible to enroll in a PNOC clinical trial you have to contact the closest participating site.