Sarcomas are cancers that develop from connective tissues in the body, such as muscles, fat, bones, the linings of joints, or blood vessels. There are many types of sarcomas.
Rhabdomyosarcoma (RMS) is a type of sarcoma made up of cells that normally develop into skeletal (voluntary) muscles. These are muscles that we control to move parts of our body.
Rhabdomyosarcoma (RMS) is classified according to the histology of the cells (how they look under a microscope).
Well before birth, cells called Rhabdomyoblasts (which will eventually form skeletal muscles) begin to form. These cells can develop into RMS. Because this is a cancer of very early forms of muscle cells, it is much more common in children, although it does sometimes occur in adults.
We might think of our skeletal muscles as being mainly in our arms and legs, but RMS can start nearly anywhere in the body, even in some parts of the body that do not normally have skeletal muscle.
The most common one is called Embryonal and the most dangerous one is called Alveolar. There are four types:
Common sites of RMS include:
MRI scan, PET/CT scan, Biopsy analysis.
Chemotherapy, Radiation, Surgery.