Ependymoma is a primary tumor, which means that it starts in either the brain or spine. The brain and spine are part of the central nervous system (CNS).
Ependymomas arise from the cells lining the ventricles (the fluid containing spaces within the brain) and central canal within the spinal cord.
Ependymomas are relatively rare tumors, accounting for 2–3% of all primary brain tumors. About 30% of pediatric ependymomas are diagnosed in children younger than three years of age. The cause is unknown.
The most common types of cells in the central nervous system are neurons and glial cells. Tumors from neurons are rare. Glial cells are the cells that support the brain. Tumors that occur from these cells are called gliomas. Glial cell subtypes of the CNS include Astrocytes, Oligodendrocytes and Ependymal cells.
Ependymoma is a class of tumor that occurs in the brain or spinal cord. It includes different subtypes and grades. It is the third most common type of childhood brain tumor.
Most children have grade II or grade III variants occurring in the brain.
Ependymomas appear in different locations within the brain and spinal column; symptoms depend on the location and size of the tumor. The biology may also be different based on the location.
CT scan (computed tomography), MRI (magnetic resonance imaging), biopsy, Lumbar puncture.
Surgery, radiation therapy (traditional and proton beam), chemotherapy.
Some treatments, while increasing survival, may have significant side effects on children. Prior to treatment, your child may undergo neuropsychological testing.
MRI scans of the brain and/or spinal cord are usually done every three to four months for the first two years following diagnosis.
Preserve patient´s life.
N/A at the moment
To understand how brain tumors develop in children and identify personalized treatment strategies visit ‘The Pacific Pediatric Neuro-Oncology Consortium (PNOC)’- http://www.pnoc.us/about